I write regarding your manuscript 'The Roles of Acidosis in Osteoclast Biology', which has been submitted to the Research Topic ‘Molecular organisation of membranes: where biology meets biophysics', as part of Frontiers in Physiology - Membrane Physiology and Membrane Biophysics.Following communications from the Topic Editor Dr. Cebecauer, it
界面显示：You are pending to respond to Reviewer 2 and Reviewer 4 and/or resubmit a new version of your manuscript.Reviewer 1 and Reviewer 3 is/are pending to respond in the discussion forum.意思是Reviewer 1 and Reviewer 3已经回复完毕？
四个审稿人一个拒稿，一个大修，两个小修，编辑给大修，但第一个审稿人最后一句话At this movement, this manuscript is not acceptable.我已经按照他的意思修改了，这个我怎么reponse呢？有模板吗？
What about the pP65 expression in Cytosolic extract? What about the transcription factor P65-NF-kB expression by EMSA in nucleolus.
On Figure 4C, the authors present a Western blot where they present GAPDH has their loading control. Unfortunately, the GAPDH blot does not