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【交流】文章解读 Nature-03212013-Article-环状RNA

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【研究进展】02142013发表在Nature 上的有关autophagy的文章

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  • clifford
    clifford  发布了新帖 02042016-Nature-Article-突触核蛋白-结构-帕金森 549天前

    02042016-Nature-Article-synuclein-Parkinson's diseaseComments' title:Disorder in the court评论题目:乱套了(法庭骚乱)Comments' abstract  The native structure of the protein α-synuclein, which is implicated in Parkinson's disease, is controversial. In-cell nuclear magnetic resonance now shows that it remains disordered when loaded into living cells.评论摘要&nbs

  • clifford
    clifford  发布了新帖 02112016-Nature-Article- 老龄化和 p16INK4a 549天前

    02112016-Nature-Article-AgeingComments' title: Out with the old评论题目:扔掉破烂Comments' abstract   The selective elimination of cells that have adopted an irreversible, senescent state has now been shown to extend the lifespan of mice and to ameliorate some age-related disease processes.评论摘要    选择性地将那些已经形成不可逆的、沉寂状态的细胞淘汰掉会使小鼠的寿命延长

  • clifford
    clifford  发布了新帖 20182016-Nature-Article-叹息的神经控制 567天前

    20182016-Nature-Article-sighing-controlTitle:The peptidergic control circuit for sighing题目:对叹息的肽能性控制回路Abstract   Sighs are long, deep breaths expressing sadness, relief or exhaustion. Sighs also occur spontaneously every few mnutes to reinflate alveoli, and sighing increases under hypoxia, stress, and certain psychiatric conditions. Here

  • clifford
    clifford  的帖子被加了1分 657天前

    02042016-Nature-Article-突触核蛋白-结构-帕金森

    02042016-Nature-Article-synuclein-Parkinson's diseaseComments' title:Disorder in the court评论题目:乱套了(法庭骚乱)Comments' abstract  The native ...
  • clifford
    clifford  发布了新帖 02042016-Nature-Article-突触核蛋白-结构-帕金森 665天前

    02042016-Nature-Article-synuclein-Parkinson's diseaseComments' title:Disorder in the court评论题目:乱套了(法庭骚乱)Comments' abstract  The native structure of the protein α-synuclein, which is implicated in Parkinson's disease, is controversial. In-cell nuclear magnetic resonance now shows that it remains disordered when loaded into living cells.评论摘要&nbs

  • clifford
    clifford  回复了帖子 中性红吞噬实验 脂多糖刺激组和空白组的吸光值无显著差异 671天前
    没做过这个实验,n年前(n>10)做过吞噬红细胞的实验(羊红细胞),恐怕帮不上你。建议:做实验很像做饭,最好是有人带,没人带的话,上网找找视频,youtube上可能有,另外你根据什么文献可以问问作者。还有,一开始先做点预实验,工作了之后(看到了被吞的--镜检)再上条件。
  • clifford
    clifford  的帖子被加了1分 673天前

    01282016-Nature-Article-非编码RNA-双RNA测序

    01282016-Nature-Article-noncoding RNA functionComments' title: Small RNA with a large impact评论题目:有大作用的小RNAComment's abstract  A simulta...
  • clifford
    clifford  发布了新帖 01282016-Nature-Article-非编码RNA-双RNA测序 674天前

    01282016-Nature-Article-noncoding RNA functionComments' title: Small RNA with a large impact评论题目:有大作用的小RNAComment's abstract  A simultaneous comparison of the RNA molecules expressed by Salmonella bacteria and human cells during infection reveals how a bacterial small RNA alters the transcript profiles of both the bacteria and the host cells.评

  • clifford
    clifford  的帖子被加了2分 679天前

    01212016-Nature-Article-大肠杆菌-密码子-简并

    01212016-Nature-Article-Codon-protein-mRNA-EcoliTitle: Codon influence on protein expression in E.coli correlates with mRNA levels题目:大肠杆菌中密码...
  • clifford
    clifford  发布了新帖 01212016-Nature-Article-大肠杆菌-密码子-简并 680天前

    01212016-Nature-Article-Codon-protein-mRNA-EcoliTitle: Codon influence on protein expression in E.coli correlates with mRNA levels题目:大肠杆菌中密码子对蛋白表达的影响与其mRNA水平具有相关性Abstract  Degeneracy in the genetic code, which enables a single protein to be encoded by a multitude of synonymous gene sequences, has an important role in regulating protein express

  • clifford
    clifford  发布了新帖 01142016-Nature-Article-癌症-ID2-VHL失活 688天前

    01142016-Nature-Article-ID2-VHL-inactivationTitle: An ID2-dependent mechanism for VHL inactivation in cancer题目:癌症中一种依赖于ID2的VHL失活作用机制Abstract  Mechanisms that maintain cancer stem cells are crucial to tumour progression. The ID2 protein supports cancer hallmarks including the cancer stem cell state. HIFα transcription factors, most notably HIF2

  • clifford
    clifford  的帖子被加了2分 693天前

    01072016-Nature-Article-肌肉干细胞与自噬

    01072016-Nature-Article-Autophagy-senescenceTitle:Autophagy maintains stemness by preventing senescence题目:干细胞会采用自噬的方式通过阻止衰老(senescence)来维持其干...
  • clifford
    clifford  发布了新帖 01072016-Nature-Article-肌肉干细胞与自噬 695天前

    01072016-Nature-Article-Autophagy-senescenceTitle:Autophagy maintains stemness by preventing senescence题目:干细胞会采用自噬的方式通过阻止衰老(senescence)来维持其干性特征(stemness)Abstract   During ageing, muscle stem-cell regenerative function declines. At advanced geriatric age, this decline is maximal owing to transition from a normal quiescence into an irrevers

  • clifford
    clifford  发布了新帖 07212016-Nature-Article-灵长类动物大脑发育转录组图谱 750天前

    Title: A comprehensive transcriptional map of primate brain development题目:灵长类动物大脑发育详细转录图谱Abstract  The transcriptional underpinnings of brain development remain poorly understood, particularly in humans and closely related non-human primates. We describe a high-resolution transcriptional atlas of rhesus monkey (Macaca mulatta) brain developmen

  • clifford
    clifford  的帖子被加了3分 969天前

    08282013-Nature-Article-人肠道微生物组学与肥胖

    08282013-Nature-Article-Microbiome-Metabolic-markers Comment’s title:   Wealth management in the gut 评论题目:胃肠道中的财富管理 Comment’s abstract...
  • clifford
    clifford  回复了帖子 求问,下面第一句话如何翻译啊?谢谢 1017天前
    “HIF-1a 的活性可以通过病毒感染诱导产生,但越来越多的证据表明诱导形成的HIF-1a 活性的最终结果是对病原体有利而不是对宿主有利的。” ----错误难免,仅供参考。
  • clifford
    clifford  的帖子被加了2分 1030天前

    12042014-Nature-Article-beta-catenin-抑郁-Dicer1-microRNA

    12042014-Nature-Article-beta-catenin-stress-resilience-Dicer1-microRNAComments’title: A molecular knife to dice depression评论题目:切碎抑郁的分子刀Comme...
  • clifford
    clifford  回复了帖子 请教悬浮细胞的MTT没有平板离心机怎么办 1031天前
    Use the key word "cytospin", you can find all what you want.
  • clifford
    clifford  发布了新帖 09242015-Nature-Review-干细胞标记物综述 1072天前

    09242015-Nature-Review-Hallmarksof pluripotency Title:Hallmarks of pluripotency 题目:干细胞万能性的标志 Abstract Stem cells self-renew and generatespe...

  • clifford
    clifford  的帖子被加了3分 1078天前

    04092014-Nature-Article-MTH1-癌症

    04092014-Nature-Article-MTH1-CancerComments’title: Damage prevention targeted评论题目:有针对性的防止损伤Comments’abstract The MTH1 protein preventsoxidiz...

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